Benadryl is an antihistamine, which means it neutralizes the histamine particles in your body.
Epinephrine given intramuscularly remains the mainstay of treatment for this condition.
Other second-line therapies, such as inhaled beta-2 agonists, H1 and H2 receptor antagonists and corticosteroids, may play a role in resolving respiratory and cutaneous signs and symptoms.
In addition, milk is slightly more acidic than plasma (p H of milk is approximately 7.2 and plasma is 7.4) allowing weakly basic drugs to transfer more readily into breast milk and become trapped secondary to ionisation.
Diphenhydramine, or its brand name Benadryl, is a medication that adults and children commonly use to reduce allergic reactions as well as allergy symptoms.
These compounds are designed to identify allergenic substances and destroy them before they cause damage to the body.
While allergies are intended to be your body’s way of protecting you, they can work against you sometimes too.
Drug transfer from maternal plasma to milk is, with rare exceptions, by passive diffusion across biological membranes.
Transfer is greatest in the presence of low maternal plasma protein binding and high lipid solubility.
Anaphylaxis is a severe, acute and potentially life-threatening condition, often in response to an allergen.
Patients experiencing anaphylaxis can present with cutaneous, respiratory, cardiovascular or gastrointestinal manifestations.
In general, children who have recently been ill will not be sedated or anesthetized.